EORTC-QLQ-LC29 Clinical Workflow

Introduction

This questionnaire is an updated of the EORTC QLQ-LC13. The EORTC QLQ-LC13 was the first module developed to be used in conjunction with the core questionnaire C30. Since the publication of the LC13 in 1994, major advances have been made in the treatment of lung cancer as well as in assessing quality of life. Therefore, the EORTC decided to support a project to update the LC13. [1]

The update of the EORTC questionnaire for assessing quality of life in lung cancer follows a rigorous methodology including patient involvement on various levels. The updated questionnaire after Phases 1 to 3 comprises, in addition to the original items, new items related to the side-effects of targeted therapies and surgery. The updated module currently undergoes full validation and psychometric testing in a cross-cultural, multicenter Phase 4 study, involving 19 centers from 12 different countries. The updated module should become the new standard for quality of life assessment in lung cancer clinical trials.

The EORTC-QLQ-LC29 flow contains the EORTC-QLQ-LC29 questionnaire and associated calculation. After form submission, the EORTC-QLQ-LC29 calculation is executed automatically. It's easy to extend this flow with conditional logic based on the interpretation of the EORTC-QLQ-LC29 calculation.

EORTC-QLQ-LC29 Questionnaire

Questions and Scoring

Click here to see the form of the EORTC QLQ-LC29

The QLQ-LC29 incorporates 5 multi-item scales to assess symptom or quality of life issues. In addition, 5 single items assess symptoms.

Scale:

• Coughing Symptom
• Shortness of Breath
• Side effects of treatment
• Fear of progression
• Surgery-related problems
• Coughing blood / Haemoptysis
• Pain in arm or shoulder
• Pain in other parts of body
• Weight loss

Remarks:

• “Item range” is the difference between the possible maximum and the minimum response to individual items. All items are scored 1 to 4, giving range = 3

Resources

[1] Update of the EORTC questionnaire for assessing quality of life in patients with lung cancer: Introducing the new EORTC QLQ-LC29. Michael Koller and EORTC Update Lung Cancer Module Group Journal of Clinical Oncology 2016 34:15_suppl, e18096-e18096